![]() ![]() ![]() One study in a cohort of anemic women aged ≥65 years found a higher incidence of ACD and renal anemia in older age. Anemia in relation to aging and sex has been studied previously, although but few studies distinguished between the various anemia etiologies. For still 26–44% of patients, the etiology of anemia is uncertain. In the Western world, four common etiologies for anemia are anemia of chronic disease (ACD) (17–40%), iron deficiency anemia (IDA) (5–19%), renal anemia (2–15%) and vitamin B12 or folic acid deficiency (2–14%). The final step is to confirm the underlying condition that is causing anemia and to treat this to prevent relapse of the anemia or a decline in clinical condition. If necessary, additional diagnostic tests can be performed (such as endoscopy) to find the cause of the anemia. The third step is to match the anemia etiology to the patient’s clinical presentation, symptoms and comorbidities. Secondly, the anemia can be further categorized into an underlying etiology based on additional laboratory analysis. In clinical practice, anemia diagnostics is a four-step process, starting with the clinical suspicion of anemia and confirmation of a decreased hemoglobin concentration in a blood test. Age, sex and the severity of anemia are predictive of the underlying etiology. ConclusionĮxtensive laboratory analysis in anemic patients from the general population helped clarify the etiology of anemia and revealed many various combinations of etiologies in a significant proportion of patients. Mild anemia was more often associated with ACD and uncertain anemia, while severe anemia was mainly seen in patients with IDA. Older age was associated with a lower incidence of IDA and a higher incidence of renal anemia. The most common single etiologies were IDA (82%) and ACD (68%), while the multiple etiologies most commonly included folic acid deficiency (94%) and suspected bone marrow disease (88%). ![]() The most common etiologies were anemia of chronic disease (ACD) (54.5%), iron deficiency anemia (IDA) (19.1%) and renal anemia (13.8%). The anemia etiology was unclear in 20% a single etiology was established in 59% and multiple etiologies in 22% of the patients. Resultsīlood of 4152 patients (median age 75 years 49% male) was analyzed. Patients were assigned one or more of these etiologies on the basis of their test results. Eight laboratory-orientated etiologies of anemia were defined. MethodĪn extensive laboratory analysis was performed in blood of newly diagnosed anemia patients aged ≥50 years from the general population in the city of Dordrecht area, the Netherlands. To study etiologies of anemia using an extensive laboratory analysis in general practices. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |